James P Hardwick's Cytochrome P450 Function and Pharmacological Roles in PDF

By James P Hardwick

ISBN-10: 0128031190

ISBN-13: 9780128031193

Cytochrome P450 functionality and Pharmacological Roles in irritation and Cancer, the newest quantity within the Advances in Pharmacology sequence, offers not just the functionality of cytochrome P450 but additionally its pharmacological roles in irritation and cancer.

  • Contains contributions from the simplest authors within the field
  • Ideal reference for these undertaking learn in melanoma, irritation, cytochrome P450, metabolism, liver sickness, and oxidative stress
  • Provides a necessary source for pharmacologists, immunologists, and biochemists

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Additional resources for Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer

Sample text

McCune, J. , Shord, S. , Hawke, R. , et al. (2002). The effect of cyclophosphamide with and without dexamethasone on cytochrome P450 3A4 and 2B6 in human hepatocytes. Drug Metabolism and Disposition, 30, 814–822. Lorr, N. , Tu, Y. , & Yang, C. S. (1982). The nature of nitrosamine denitrosation by rat liver microsomes. Carcinogenesis, 3, 1039–1043. CYPs in Carcinogen and Chemotherapeutic Drug Metabolism 29 Lu, A. , & Coon, M. J. (1968). Role of hemoprotein P-450 in fatty acid omegahydroxylation in a soluble enzyme system from liver microsomes.

The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms. Pharmacology and Therapeutics, 46, 297–308. Meyer, U. , & Zanger, U. M. (1997). Molecular mechanisms of genetic polymorphisms of drug metabolism. Annual Review of Pharmacology and Toxicology, 37, 269–296. , & Wang, M. Z. (2014). The revised human liver cytochrome P450 “pie”: Absolute protein quantification of CYP4F and CYP3A enzymes using targeted quantitative proteomics. Drug Metabolism and Disposition, 42, 1241–1251.

Conney, A. , Brown, R. , Miller, J. , & Miller, E. C. (1957). The metabolism of methylated aminoazo dyes. VI. Intracellular distribution and properties of the demethylase system. Cancer Research, 17, 628–633. Conney, A. , Miller, E. , & Miller, J. A. (1956). The metabolism of methylated aminoazo dyes. V. Evidence for induction of enzyme synthesis in the rat by 3-methylcholanthrene. Cancer Research, 16, 450–459. Conney, A. , Miller, E. , & Miller, J. A. (1957). Substrate-induced synthesis and other properties of benzpyrene hydroxylase in rat liver.

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Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer by James P Hardwick

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