Read e-book online Comparative Physiology of the Vertebrate Kidney PDF

By William H. Dantzler

ISBN-10: 364283521X

ISBN-13: 9783642835216

ISBN-10: 3642835236

ISBN-13: 9783642835230

This quantity emphasizes the comparative method of lower thanĀ­ status vertebrate renal functionality. i'm confident that this method is of specific worth in realizing either the main points of renal functionality on the mobile and subcellular degrees and the renal function in regulating fluid volumes and solute concentrations. My publicity to this procedure first happened in the course of a pupil examine event within the laboratory of Wilbur H. Sawyer, who additionally supplied an advent to the works of Homer W. Smith and August Krogh. the significance of this procedure used to be bolstered via doctoral and postdoctoral learn within the laboratory of Bodil Schmidt-Nielsen. it's been proven via years of private event due to the fact that then. My examine and my figuring out of renal functionality were aided over the years via collaboration and dialogue with quite a few scholars and co-workers. Of specific imporĀ­ tance in constructing my perspectives on comparative renal functionality, and particularly at the courting of constitution to operate, has been my lengthy organization with my colleague and buddy, Eldon J. Braun. Donald S. Farner, who instructed the writing of this quantity, supplied precious editorial tips. a lot of my own examine during this quarter has been supported through the years by way of delivers from the USA nationwide technology beginning and nationwide Institutes of wellbeing and fitness. The writing of this quantity used to be accomplished whereas i used to be in Wiirzburg, Federal Republic of Germany, supported by means of a Senior U.S. Scientist Award from the Alexander von Humboldt Foundation.

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Of course, other combinations are also possible. It is not known whether any mammalian-type nephrons that are not filtering are small, transitional nephrons with short loops of Henle or larger nephrons with long loops. 4). 3), about 72% of the mammalian-type nephrons must now be filtering. As discussed above for other nonmammalian vertebrates, regulation of the whole-kidney GFR in birds by altering the number of filtering reptilian-type nephrons appears practical because these nephrons empty at right angles into collecting ducts and apparently cannot function in concert to contribute directly 45 to the urine-concentrating mechanism.

Tigrinurn than in N. rnaculosus . Neither species has the large amplification and intercellular interdigitation of the lateral cell membranes observ~d in mammals (see Fig. 12). (After Maunsbach and Boulpaep 1984) Fig. 14 A-F. Schematic drawings showing characteristics of surfaces of proximal and distal tubule cells of mammals and reptiles. A Mammalian proximal cell type (Jess detailed than in Fig. 12). ) proximal cell type. Note amplification of basal surface area. ) proximal cell type . Note lack of amplification of basal surface area.

Rich intercalated cells (Fig. 15; also Stanton et al. 1984a). The transition from the distal tubule into the collecting tubule is gradual with increasing numbers of intercalated and principal cells occurring toward the end of the distal tubule (Fig. 15; also Stanton et al. 1984a). Such a gradual transition from the distal tubule through the connecting tubule also occurs in the mammalian kidney. Among fishes, intercalated cells are found only in the collecting tubules of primitive lampreys, Polypteri, and lung fish (Hentschel and Elger 1987).

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Comparative Physiology of the Vertebrate Kidney by William H. Dantzler

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