"While the APA’s Textbook of habit Psychiatry covers fabric basic psychiatrist or fundamental care health practitioner wishes for the perfect referral and preliminary administration of stimulant dependence, Cocaine and Methamphetamine Dependence: Advances in therapy is going past this simple wisdom and addresses the quick evolution of either the knowledge and the therapy of stimulant abusers. It additionally sheds mild on how the epidemiology of cocaine, amphetamine and methamphetamine abuse and dependence have huge changes in geographic distribution either right here and out of the country, and the way remedies are evolving to assist those complicated sufferers make the most of rising pharmacological and behavioral therapies."
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Extra resources for Cocaine and Methamphetamine Dependence
Clinical observations. Arch Gen Psychiatry 43:107–113, 1986 Glasner-Edwards S, Mooney LJ, Marinelli-Casey P, et al: Identifying methamphetamine users at risk for major depressive disorder: findings from the Methamphetamine Treatment Project at three-year follow-up. Am J Addict 17:99–102, 2008 Graham JK, Hanzlick R: Accidental drug deaths in Fulton County, Georgia, 2002: characteristics, case management and certification issues. Am J Forensic Med Pathol 29:224–230, 2008 Hughes JR, Hatsukami DK, Mitchell JE, et al: Prevalence of smoking among psychiatric outpatients.
2003). Interestingly, this neural circuit may be critical in drug-seeking behaviors because systemically administered prazosin reduces cocaine-induced reinstatement of cocaine self-administration and prevents the enhancement of cocaine self-administration in animals with prior drug exposure (Kalivas and McFarland 2003; X. Y. Zhang and Kosten 2005, 2007). Effects on Glutamate Neurotransmission As shown for DA and NE, studies indicate GLU neurotransmission also plays a significant role in drug reward and reinforcement (Figure 2–3) and may offer still another therapeutic target for the treatment of cocaine dependence (Bowers et al.
2008). Medical debility secondary to major cardiovascular events and drug-related disease transmission related to cocaine use stress social and care management resources (Degenhardt et al. 2011). Indeed, cocaine is certainly the most deadly of all the street-acquired stimulants. Evidence-based ranking of each drug of abuse, using categories that included physical harm, dependence, and social harm as criteria, listed cocaine second only to the opioid heroin (Figure 2–6) (Nutt et al. 2007). Despite considerable effort to prevent transport of cocaine across borders, it is still readily available.
Cocaine and Methamphetamine Dependence