Download e-book for kindle: Bipolar Depression: A Comprehensive Guide by S. Nassir Ghaemi, Rif S. El-Mallakh

By S. Nassir Ghaemi, Rif S. El-Mallakh

ISBN-10: 1585621714

ISBN-13: 9781585621712

Even though melancholy is the commonest presentation of bipolar sickness, right prognosis quite often calls for a background of mania and hence offers a powerful problem. This booklet presents clinicians with the mandatory counsel to tell apart this disorder and pursue a suitable healing direction. It brings jointly a group of medical investigators who supply state of the art examine at the subject and deal with the main severe matters concerning its remedy. Bipolar melancholy first introduces a hierarchical version for prognosis to permit the clinician to differentiate among bipolar and unipolar melancholy, addressing difficulties of misdiagnosis and overdiagnosis in addition to differentiating attention-deficit/hyperactivity affliction (ADHD) and bipolar affliction. Early chapters evaluate the neurobiology and genetics of this hugely heritable , featuring reviews of neurotransmitter functionality and mind imaging reviews and documenting the susceptibility of particular chromosomes as loci for bipolar disease. different chapters deal with the actual problems with bipolar melancholy in youngsters, for whom a analysis is mainly challenging, and suicide, concentrating on the necessity for overview in the course of either acute and upkeep remedy with interventions acceptable to a patient's signs and heritage. Bipolar melancholy deals reviews of particular therapy techniques: -Lithium and antiepileptic medicines: that includes a overview of the latest learn at the use of lithium, within which better doses are proven to be powerful, plus insurance of lamotrigine, valproic acid, carbamazepine, oxcarbazepine, and topiramate. -Antidepressants: providing new views on a fancy box, together with a dialogue of the randomized medical trial literature and observational experiences on their use, and mentioning cautions concerning unwanted effects. -Antipsychotics: comparing the variation among first- and second-generation medicinal drugs and discussing their position in controlling acute depressions. -Novel techniques to therapy: together with using strange neuroleptics, electroconvulsive treatment, transcranial magnetic stimulation, vagus nerve stimulation, ketogenic nutrition, omega-3 fatty acids, myo-inositol, and dopamine agonists. -Psychological interventions: targeting the inclusion of cognitive-behavioral remedy or interpersonal social rhythm treatment for nonmelancholic depressions in sufferers who had formerly bought psychoeducation. regardless of the previous decade's advances in perform and study, there is still a lot room for development in knowing and treating bipolar melancholy. This ebook blazes a path towards that aim, commencing new doorways in spotting ameliorations among bipolar and unipolar different types of melancholy whereas supplying either researchers and clinicians key insights into this troubling disease.

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Br J Psychiatry 175:537–543, 1999 Baldessarini RJ, Faedda GL, Hennen J: Risk of mania with antidepressants. Arch Pediatr Adolesc Med 159:298, 2005 Benazzi F: Prevalence and clinical features of atypical depression in depressed outpatients: a 467-case study. Psychiatry Res 86:259–265, 1999 Benazzi F: Borderline personality disorder and bipolar II disorder in private practice depressed outpatients. Compr Psychiatry 41:106–110, 2000 Benazzi F: The clinical picture of bipolar II outpatient depression in private practice.

Pittsburgh, PA, Blackwell Munksgaard, 2003, p 33 Birnbaum RJ: Borderline, bipolar, or both? Harv Rev Psychiatry 12:146–149, 2004 Bolanos CA, Barrot M, Berton O, et al. Methylphenidate treatment during preand periadolescence alters behavioral responses to emotional stimuli at adulthood. Biol Psychiatry 54:1317–1329, 2003 Bolton S, Gunderson JG: Distinguishing borderline personality disorder from bipolar disorder: differential diagnosis and implications. Am J Psychiatry 153:1202–1207, 1996 Bowden C, Brugger A, Swann A, et al: Efficacy of divalproex vs lithium and placebo in the treatment of mania.

In contrast, only about 25% of those who presented with ADHD met criteria for bipolar disorder (Wozniak et al. 1995). Thus, it appears that many Diagnosis of Bipolar Depression 23 children are diagnosable with ADHD alone and seem to respond well to stimulants, while some children who appear to have ADHD may in fact have bipolar disorder. 5% of adults with bipolar disorder can be retrospectively diagnosable with ADHD in childhood (Nierenberg et al. 2005). The use of stimulants, while not diagnostic, can be informative in the setting of other possible manic symptoms and a family history of bipolar disorder.

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Bipolar Depression: A Comprehensive Guide by S. Nassir Ghaemi, Rif S. El-Mallakh


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